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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC1L
All Species:
15.45
Human Site:
S446
Identified Species:
28.33
UniProt:
Q13415
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13415
NP_004144.2
861
97350
S446
V
S
R
N
L
R
S
S
L
K
S
S
L
H
T
Chimpanzee
Pan troglodytes
XP_513408
861
97367
S446
V
S
R
N
L
R
S
S
L
K
S
S
L
H
T
Rhesus Macaque
Macaca mulatta
XP_001111614
860
97440
S445
V
S
R
N
L
R
S
S
L
K
S
S
L
Y
T
Dog
Lupus familis
XP_532575
858
97161
S444
V
S
R
D
P
S
S
S
M
K
S
S
L
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1N2
840
95057
G425
L
P
T
R
N
S
L
G
Q
S
R
T
R
Q
T
Rat
Rattus norvegicus
Q80Z32
848
95741
A433
Q
S
R
T
R
R
T
A
S
K
P
S
S
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026457
858
96850
P444
T
P
K
S
S
R
K
P
S
V
H
T
P
A
K
Frog
Xenopus laevis
NP_001081806
886
99953
T472
R
G
C
A
T
P
R
T
P
T
S
S
R
K
T
Zebra Danio
Brachydanio rerio
NP_956227
910
101179
V495
R
A
T
D
K
S
C
V
S
A
R
T
P
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O16810
924
103263
I510
A
T
T
P
S
K
G
I
T
T
A
T
A
T
P
Honey Bee
Apis mellifera
XP_392056
490
55682
T92
Q
Q
K
T
H
L
N
T
P
K
S
H
S
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798977
905
100707
L483
A
T
K
M
P
T
V
L
I
V
D
E
L
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567440
809
91877
I406
E
K
V
G
M
K
R
I
P
E
H
V
R
C
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.7
81.5
N.A.
66
69.8
N.A.
N.A.
50.5
52.4
48.6
N.A.
33.4
31.8
N.A.
29.7
Protein Similarity:
100
98.9
97.3
88.8
N.A.
77.9
79.9
N.A.
N.A.
66.3
67
63.1
N.A.
52.7
43.5
N.A.
47.1
P-Site Identity:
100
100
93.3
66.6
N.A.
6.6
40
N.A.
N.A.
6.6
20
0
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
20
53.3
N.A.
N.A.
26.6
26.6
20
N.A.
26.6
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
8
0
0
0
8
0
8
8
0
8
8
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
0
0
16
0
% C
% Asp:
0
0
0
16
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
16
8
0
16
8
% H
% Ile:
0
0
0
0
0
0
0
16
8
0
0
0
0
8
0
% I
% Lys:
0
8
24
0
8
16
8
0
0
47
0
0
0
8
24
% K
% Leu:
8
0
0
0
24
8
8
8
24
0
0
0
39
0
8
% L
% Met:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
24
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
8
16
8
0
8
24
0
8
0
16
0
8
% P
% Gln:
16
8
0
0
0
0
0
0
8
0
0
0
0
24
0
% Q
% Arg:
16
0
39
8
8
39
16
0
0
0
16
0
24
0
0
% R
% Ser:
0
39
0
8
16
24
31
31
24
8
47
47
16
0
0
% S
% Thr:
8
16
24
16
8
8
8
16
8
16
0
31
0
8
54
% T
% Val:
31
0
8
0
0
0
8
8
0
16
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _